Just in time for the upcoming respiratory virus season, a new trial indicates that co-administered vaccines are safe and effective for older adults.

Specifically, the researchers concluded that the adjuvanted influenza and respiratory syncytial virus (RSV) vaccines studied could be given together in adults aged 65 and older without negatively interfering with the immune response of either vaccine. The trial involved 1,045 participants, 523 of whom received  RSV and flu vaccines simultaneously, while the remainder received the two shots a month apart. Both study groups included people with medically stable comorbidities such as diabetes and hypertension. The most common side effects were injection site pain, fatigue, and myalgia in both groups.

Investigators observed, “Given the seasonal overlap of these two infections, the ability to give both vaccines during a single…visit may improve convenience and increase uptake of both vaccines, ultimately reducing the high burden of both influenza and RSV disease among older adults.” 

These findings present an opportunity for vaccine education, particularly at a time when vaccination rates are waning. According to another report, only 29.1% of people over age 65 had gotten the RSV vaccine as of May 4 this year. At the same time, only 50% got a flu shot in the 2023–2024 season as of February 24. There are many possible reasons for these numbers, including low awareness of RSV and its potential danger to older adults as well as uncertainties about the safety and effectiveness of RSV vaccines.

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